The couple tied the knot on Sunday night in Mt. Pleasant, S.C., a source confirmed to People.
Reynolds, 35, and Lively, 25, were first romantically linked about one year ago. The two co-starred in the 2011 superhero flick Green Lantern.
This is the second marriage for Reynolds. The Canadian actor was previously married to Scarlett Johanson. Their divorce was finalized in 2011.